17-hydroxyiminoalkyl and 17-hydroxyiminomethylalkenyl cyclopenta

Details 17-hydroxyiminoalkyl and 17-hydroxyiminomethylalkenyl cyclopenta 17-hydroxyiminoalkyl and 17-hydroxyiminomethylalkenyl cyclopenta

1996-05-17

1998-08-11

Prior, Kimberly J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514182, 540107, 540108, 540112, 552552, 552554, 552555, 552600, 552601, 552606, 552607, 552609, 552611, C07J 4100, C07J 4300, A61K 3158, A61K 31575

Patent

active

057927596

ABSTRACT:
Novel 17-hydroxyiminoalkyl and 17-hydroxyiminomethylalkenyl steroids of the general formula (I) ##STR1## where A, R.sup.1 and R.sup.2 are defined in the specification are disclosed. The compounds have cardiovascular activity. Pharmaceutical compositions containing compounds of formula (I) are also disclosed for the treatment of heart failure and hypertension.

REFERENCES:
patent: 4490296 (1984-12-01), Barton et al.
patent: 5324719 (1994-06-01), Frigerio et al.
patent: 5444055 (1995-08-01), Cerri et al.
patent: 5538960 (1996-07-01), Cerri et al.
patent: 5583127 (1996-12-01), Cerri et al.
patent: 5599806 (1997-02-01), Cerri et al.

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