17-Hydroxy-steroids

Details 17-Hydroxy-steroids 17-Hydroxy-steroids

1987-11-25

1990-02-06

Sneed, H. M. S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

540 94, C07J 900

Patent

active

048986941

ABSTRACT:
Compounds of the formulae: ##STR1## are useful as anti-cancer, anti-obesity, anti-diabetic, anti-coronary agents, anti-aging agents, anti-hypolipidemic agents and anti-autoimmune agents.

REFERENCES:
patent: 2232735 (1941-02-01), Schoeller et al.
patent: 2243887 (1941-06-01), Serini et al.
patent: 2266778 (1941-12-01), Logemann et al.
patent: 2267257 (1941-12-01), Ruzicka
patent: 2267258 (1941-12-01), Ruzicka
patent: 2312344 (1943-03-01), Logemann
patent: 2357364 (1944-09-01), Stavely
patent: 2368199 (1945-01-01), Butenandt et al.
patent: 2833793 (1958-05-01), Dodson et al.
patent: 2838500 (1958-06-01), Campbell et al.
patent: 2844602 (1958-07-01), Ringold et al.
patent: 2911418 (1959-11-01), Johns et al.
patent: 2927119 (1960-03-01), Ellis et al.
patent: 2936312 (1960-05-01), Babcock et al.
patent: 2969379 (1961-01-01), Babcock et al.
patent: 3082223 (1963-03-01), Bowers et al.
patent: 3148198 (1964-09-01), Goldkamp
patent: 3176030 (1965-03-01), Huffman
patent: 3187023 (1965-06-01), Robinson
patent: 3189624 (1965-06-01), Fried et al.
patent: 3200113 (1965-08-01), Christiansen et al.
patent: 3254099 (1966-05-01), Jolles et al.
patent: 3257428 (1966-06-01), Klimstra
patent: 3282969 (1966-11-01), Boswell, Jr.
patent: 3310470 (1967-03-01), Schulze et al.
patent: 3357888 (1967-12-01), Campbell et al.
patent: 3380886 (1968-04-01), Campbell et al.
patent: 3391166 (1968-07-01), Klimstra
patent: 3463798 (1969-08-01), Godtfredsen et al.
patent: 3471480 (1969-10-01), Fritsch et al.
patent: 3501504 (1970-03-01), Klimstra
patent: 3505364 (1970-04-01), Mehrhof et al.
patent: 3716530 (1973-02-01), Krubiner
patent: 3976691 (1976-08-01), Middleton et al.
patent: 4344941 (1982-08-01), Weichert et al.
patent: 4628052 (1986-12-01), Peat et al.
Chang et al., "The Anabolic and Androgenic Activities of 17-alpha-methytestosterone and Related Steroids in Castrated Rats and Mice", Chem. Absts., 62:4295h, (1965).
Bernassau et al., "Circular Dichroism of Olefins. IV. A Semiquantititative Paredictaion of the Intensity of the Cotton Effect of Allyl Alcohols and Ethers", Chem. Absts., 92:181401.
Beloeil et al., "Stereochemistry of Gaseous Anions: OH-Negative Chemical Ionization of 17-R-5-Alpha, 14-Beta-Androstant-14,17-Diol", J. Am. Chem. Soc., 105:1355-1359, (1983).
Martin Bohl, "Molecular Mechanics Investigation on Side-Chain Conformations of a 17-Alpha-ethyl-17-Beta-Hydroxy Steroid with Regard to Receptor Binding", Chem. Absts., 107:33341, (1987).
Hanson et al., Perkin Transactions I, (1977), pp. 499-501.
Chemical Abstracts, 89, 1058656, (1978).
Numazawa et al., Steroids, 32, 519-527, (1978).
Abou-Gharbia et al., Journal of Pharmaceutical Sciences, 70, 1154, (1981).
Pashko et al., Carcinogenesis, 2, 717-721, (1981).
Pashko et al., Carcinogenesis, 5, 463-466, (1984).
Raineri and Levy, Biochemistry, 9, 2233, (1970).
Robinson et al., J. Org. Chem., 28, 975, (1963).
Neef et al., J. of Org. Chem., 43, 4679-4680, (1978).
Gordon et al., Cancer Research, 46, 3389-3395, (1986).
Julian et al., in JACS, 70, 3872-3876, (1948).
Ross et al., in J. Chem. Soc., 25, (1945).
Denny et al., J.C.S. Perkin I, 486-492.
Shoppe et al., J. Chem. Soc. C., 2767, 2770, (1969).
Kirk, J.C.S. Perkin I, 787, (1980).
Numazawa et al., Steroids, 385, 403, (1985).

Affiliated with

Also associated with

Rating

17-Hydroxy-steroids does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 17-Hydroxy-steroids, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 17-Hydroxy-steroids will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-440696