17-Cyclobutylmethyl-3-hydroxy-.beta.-methyl-6-methylene morphina

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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546 75, A61K 31485, C07D22128

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active

042593298

ABSTRACT:
Disclosed are 6-methylene-morphinan compounds corresponding to the formula: ##STR1## wherein R.sub.1 and R.sub.3 are H or methyl and R.sub.2 is cyclopropylmethyl or cyclobutylmethyl. These compounds are useful as mixed analgesics
arcotic antagonists.

REFERENCES:
patent: 3285922 (1966-11-01), Gates, Jr.
patent: 3654280 (1972-04-01), Sawa et al.
patent: 3738989 (1973-06-01), Sawa et al.
Sawa et al., Tetrahedron, vol. 24, pp. 255-260 (1968).

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