Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1975-02-25
1976-08-31
Roberts, Elbert L.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
2602395, 2603974, 26039745, 2603975, 424243, C07D47100
Patent
active
039780481
ABSTRACT:
Steroidal compounds of the invention bear a 17.beta.-oxygenated group and a 17.alpha.-.PSI.-alkyl substituted allene group, e.g., 17.alpha.-(penta-1'-2'-dienyl)-estra-4,9-dien-17.beta.-ol-3-one, and are prepared by a procedure, e.g., involving reacting a corresponding intermediate bearing a 17.alpha.-(3'-dialkylamino-3'-alkyl-substituted-1'-propynyl)-group with a complex hydride. The steroidal compounds are useful as pharmaceuticals, e.g., as progestational agents.
REFERENCES:
patent: 3888849 (1975-06-01), Bacso
Roberts Elbert L.
Sandoz Inc.
Sharkin Gerald D.
Vila Richard E.
Weinfeldt Frederick H.
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