Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai
Patent
1998-05-29
1999-10-05
Dees, Jose' G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Cyclopentanohydrophenanthrene ring system doai
514182, 552520, A61K 3156, C07J 4100
Patent
active
059624442
ABSTRACT:
The invention is directed to 17.beta.-nitro-11.beta.-arylsteroids of formula I: ##STR1## wherein R.sup.1, R.sup.6, R.sup.7, R.sup.12 and X are as defined by the specification. The compounds exhibit potent antiprogestational activity and are useful in the treatment of fibroids, endometriosis, cervical ripening prior to delivery, hormone replacement therapy and in the control of fertility.
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Bartley Gary S.
Cook C. Edgar
Kepler John A.
Lee David Yue-wei
Shetty Rupa S.
Badio Barbara
Dees Jos,e G.
Research Triangle Institute
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