17.beta.-hydroxybenzoyl-4-aza-5.alpha.-androst-1-en-3-ones as te

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 3.40 ] – good Voters 3   Comments 3

Details

546 77, A61K 3158, C07J 7300

Patent

active

050989081

ABSTRACT:
Novel 17.beta.-hydroxybenzoyl-4-aza-5.alpha.-androst-1-en-3-ones as tetosterone reductase inhibitors of the formula: ##STR1## wherein R is selected from hydrogen, methyl and ethy and

REFERENCES:
patent: 2227876 (1941-07-01), Bolt
patent: 3239417 (1966-03-01), Di Tullio et al.
patent: 3264301 (1966-08-01), Doorenbos et al.
patent: 3285918 (1966-11-01), Doorenbos et al.
patent: 4220775 (1980-02-01), Rasmusson et al.
patent: 4317817 (1982-03-01), Blohm et al.
patent: 4377584 (1983-03-01), Rasmusson et al.
patent: 4732897 (1988-03-01), Cainelli et al.
patent: 4760071 (1988-07-01), Rasmusson et al.
patent: 4845104 (1989-07-01), Carlin et al.
patent: 4859681 (1989-08-01), Rasmusson et al.
patent: 4882319 (1989-11-01), Holt et al.
patent: 4888336 (1989-12-01), Holt et al.
patent: 4910226 (1990-03-01), Holt et al.
Endo, vol. 91, No. 2 (1972) by Neri, et al., pp. 427-437.
Steroids, 14, 269 (1969), by Nayfeh, et al.
Endo, vol. 92, p. 1216 (1973) by Voigt and Hsia.
J. Pharm. Sci., 62, 4, pp. 638-640 (1973) by Doorenbos and Solomons.
J. Pharm. Sci., 60, 8, pp. 1234-1235 (1971), by Doorenbos and Brown.
J. Pharm., 63, 4, pp. 620-622 (1974) by Doorenbos and Kim.
J. Med. Chem. (1986) 29 (11): pp. 2298-3115 by Rasmusson et al.
Prostate (1986) (1): pp. 65-75 by Brooks et al.
Steroids (1986) 47 (1): pp. 1-19 by Brooks et al.
Endocr. (1985) 117 (2): pp. 571-9, by Liang et al.
J. Med. Chem. (1984) 27 (12): pp. 1690-1701, by Rasmusson et al.
J. Org. Chem. (1981) vol. 46, No. 7, pp. 1442-1446 by Back.
Chem. Abstracts, vol. 95, 109055j, by T. Liang et al.
JNCI, vol. 74, No. 2, pp. 475-481 (Feb. 1985), by Kadahoma et al.
The Prostate, vol. 10, pp. 189-197 (1987) by G. L Andriole et al.
J. Endocr., vol. 57, pp. 111-121 (1973), by K. D. Bingham et al.
Toxicol. Appl. Pharmacol., vol. 103, pp. 222-227 (1990), by G. L. Kedderis et al.
Bioinorganic Chemistry, 17, pp. 372-376 (1986) by B. W. Metcalf et al.
Biochemistry, 1990, vol. 29, pp. 2815-2824, by M. A. Levy et al.
J. Med. Chem., 1990, vol. 33, pp. 943-950, D. A. Holt et al.
J. Steroid Biochem., vol. 34, Nos. 1-6, pp. 571-575 (1989), by M. A. Levy et al.
J. Med. Chem., vol. 33, pp. 937-942 (1990) by D. A. Holt et al.
TIPS, Dec. 1989, vol. 10, pp. 491-495, by D. W. Metcalf et al.
Steroids, vol. 35, No. 3 (Mar. 1980), p. 1-7.
Prostate, vol. 9, pp. 311-318 (1986) by N. Stone et al.
Steroids, vol. 47, No. 1, pp. 1-19 (1986) by J. R. Brooks et al.
Lancet, Nov. 1986, No. 8515, pp. 1095-1096 by Labrie et al.
J. Clin. Endocrin. and Metab., vol. 55, No. 1, pp. 188-193 (1987) by Rittmaster et al.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

17.beta.-hydroxybenzoyl-4-aza-5.alpha.-androst-1-en-3-ones as te has received 3 rating(s) and 3 review(s), resulting in an average rating of 3.40 on a scale from 1 to 5. The overall rating for this patent is good.

If you have personal experience with 17.beta.-hydroxybenzoyl-4-aza-5.alpha.-androst-1-en-3-ones as te, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 17.beta.-hydroxybenzoyl-4-aza-5.alpha.-androst-1-en-3-ones as te will most certainly appreciate the feedback.

Rate now

Gabby

I am a software house nmaager and I express that software patents refrain innovation by registering ideas and don't give a chance to european EUA independent develloped software solutions.

Was this review helpful to you?

Rate originality.
If you were patent examiner would you approve this patent?
How useful is this invention?
What is the true purpose of this patent?
Is it obsolete or futuristic?
Does this invention solve a specific problem?

0     0    


Asdrianny

Total cost for a seat set like the one you mention is as oollfws:$225 for the Set, cut and covered$20 for the 2-tone fabric$37.50 for the Kanji logos (3@ $12.50 each)$15.00 for the Hayabusa Name$120.00 to light up the logos (4@$30 each)$15.00 Standard Ground ShippingTOTAL $432.50

Was this review helpful to you?

Is it obsolete or futuristic?
What is the true purpose of this patent?
If you were patent examiner would you approve this patent?
How useful is this invention?
Rate originality.
Does this invention solve a specific problem?

0     0    


Asdrianny

Total cost for a seat set like the one you mention is as oollfws:$225 for the Set, cut and covered$20 for the 2-tone fabric$37.50 for the Kanji logos (3@ $12.50 each)$15.00 for the Hayabusa Name$120.00 to light up the logos (4@$30 each)$15.00 Standard Ground ShippingTOTAL $432.50

Was this review helpful to you?

Rate originality.
What is the true purpose of this patent?
If you were patent examiner would you approve this patent?
Is it obsolete or futuristic?
How useful is this invention?
Does this invention solve a specific problem?

0     0    


     

Profile ID: LFUS-PAI-O-2010418

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.