17.beta.-Ethynyl-3,17.alpha.-estradiol and derivatives thereof

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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2603975, 26023955R, 2603974, A61K 3156

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active

040228924

ABSTRACT:
17.beta.-ethynyl-3,17.alpha.-estradiol and derivatives thereof are prepared by epimerization of 17-acyl esters of 17.alpha.-ethynyl-3,17.beta.-estradiol 3-ethers. 17.alpha.-ethynyl-3,17.alpha.-estradiol and its derivatives are active as post-coital antifertility agents and inhibit the growth of or reduce the size of the prostate gland and the seminal vesicle.

REFERENCES:
patent: 3755573 (1973-08-01), Berman
patent: 3983112 (1976-09-01), Kanojia
Steroids - by Fieser et al. pp. 476 and 591 relied on.
Chem. Abstracts (1969) vol. 70 par. 103,417r relied on.

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