17.beta.-(cyclopropylamino)androstene derivatives

Details 17.beta.-(cyclopropylamino)androstene derivatives 17.beta.-(cyclopropylamino)androstene derivatives

1989-06-14

1991-12-24

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Cyclopentanohydrophenanthrene ring system containing

514177, 514182, C07J 4100

Patent

active

050754645

ABSTRACT:
This invention is directed to 17.beta.-(cyclopropylamino)androstenes and also to a method for using such compounds in the treatment of androgen-dependent disorders. The compounds are prepared by the hydride reduction of an appropriate steroidal imine or enamine.

REFERENCES:
patent: 3097200 (1963-07-01), Kincl
patent: 3107254 (1963-10-01), Lednicer
patent: 4477445 (1984-10-01), Philibert et al.
Davis et al., Chem. Soc., C, Org., 19, 1688 (1966).
B. J. Taylor, M. S. Thesis, Massachusetts Institute of Technology, 1985, pp. 2, 24-26.

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