17 .alpha.-(substituted-methyl)-17.beta.-hydroxy/esterified hydr

Details 17 .alpha.-(substituted-methyl)-17.beta.-hydroxy/esterified hydr 17 .alpha.-(substituted-methyl)-17.beta.-hydroxy/esterified hydr

1988-07-25

1989-08-29

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514179, 26039745, 540 94, A61K 3158, A61K 3156, C07J 100, C07J 1700

Patent

active

048617636

ABSTRACT:
Steroids of the formula: ##STR1## which are characterized by a 17.alpha.-cyanomethyl, azidomethyl, methoxymethyl, phenylmethyl, or ethynylmethyl substituent and a 17.beta.-hydroxy/esterified hydroxy substitutent. The steroids of this invention have glucocorticoid, anti-glucocorticoid, progrestational, or anti-progestational activity, depending on the particular structure.

REFERENCES:
patent: 4233296 (1980-11-01), Teutsch
patent: 4774236 (1988-09-01), Cook et al.

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