17-Alkylthio (and arylthio)-1',2',3',4'-tetrahydroandrosteno [16

Details 17-Alkylthio (and arylthio)-1',2',3',4'-tetrahydroandrosteno [16 17-Alkylthio (and arylthio)-1',2',3',4'-tetrahydroandrosteno [16

1977-05-12

1978-05-23

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603973, C07J 100

Patent

active

040910369

ABSTRACT:
pg,1 Steroids having the formula ##STR1## wherein X is ##STR2## R.sub.1 is alkyl, aryl or acyloxyalkyl; R.sub.2 and R.sub.3 are the same or different and are hydrogen, alkyl, alkoxy, carboalkoxy, formyl, ##STR3## hydroxy, halogen, phenyl or cyano, with the proviso that when R.sub.2 and R.sub.3 are different, one of R.sub.2 and R.sub.3 is hydrogen; R.sub.4 is carbonyl, .beta.-hydroxymethylene or .beta.-acyloxymethylene; R.sub.5 is hydrogen or halogen; and R.sub.6 is hydrogen or fluorine; can be used as antiinflammatory agents.

REFERENCES:
patent: 3937720 (1976-02-01), Varmi et al.
patent: 3944584 (1976-03-01), Chao et al.
patent: 3971773 (1976-07-01), Cimarusti et al.
patent: 3994935 (1976-11-01), Varmi et al.

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