16002 Molecules and uses therefor

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease

Reexamination Certificate

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C536S023200

Reexamination Certificate

active

07094587

ABSTRACT:
The invention provides isolated nucleic acids molecules, designated 16002 nucleic acid molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 16002 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 16002 gene has been introduced or disrupted. The invention still further provides isolated 16002 proteins, fusion proteins, antigenic peptides and anti-16002 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.

REFERENCES:
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Lawson, N.D., et al., “Mus Musculus Calcium/Calmodulin Dependent Protein Kinase Kinase Alpha (Camkk) mRNA, Complete Cds,” Nov. 16, 1999, (sequence) GenBank [online] Bethesda, MD, USA: National Center for Biotechnology Information [retrieved on Dec. 14, 2005]. Retrieved from the Internet: URL: www.ncbi.nlm.nih.gov/>. GenBank Accession No. AF117384.
Fujisawa, H., et al., “Rattus norvegicusmRNA for Ca/Calmodulin-Dependent Protein Kinase Kinase Alpha, CaM-Kinase Kinase Alpha, Complete Cds,” Feb. 24, 1999, (sequence) GenBank [online] Bethesda, MD, USA: National Center for Biotechnology Information [retrieved on Dec. 14, 2005]. Retrieved from the Internet: URL: www.ncbi.nlm.nih.gov/>. GenBank Accession No. AB023658.
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Tokumitsu, Hiroshi, et al, “Ca2+/Calmodulin-Dependent Protein Kinase Kinase,” Sep. 15, 1995 (sequence) GenPept [online] Bethesda, MD, USA: National Center for Biotechnology Information [retrieved on Dec. 14, 2005]. Retrieved from the Internet: URL: www.ncbi.nlm.nih.gov/>. GenPept Accession No. AAC42070.
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Okuno, Sachiko., et al., “Ca2+/Calmodulin-Depedent Protein Kinase IV Kinase Isoform; CaM-Kinase Kinase Alpha [Rattussp.],” Feb. 11, 1997, (sequence) GenPept [online] Bethesda, MD, USA: National Center for Biotechnology Information [retrieved on Dec. 14, 2005]. Retrieved from the Internet: URL: www.ncbi.nlm.nih.gov/>. GenPept Accession No. AAB46910.
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Tokumitsu, Hiroshi, et al., “Calcium/Calmodulin-Dependent Protein Kinase Kinase 1 (Calcium/Calmodulin-Dependent Protein Kinase Kinase Alpha) CaM-Kinase Kinase Alpha) (CaM-KK alpha) (CaMKK Alpha) (alpha CaMKK) (CaMKK 1) (CaM-Kinase IV Kinase),” Created Feb. 1, 2005, (sequence) GenPept [online] Bethesda, MD, USA: National Center for Biotechnology Information [retrieved on Dec. 14, 2005]. Retrieved from the Internet: URL: www.ncbi.nlm.nih.gov/>. GenPept Accession No. P97756.

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