16-substituted-6-aza-androsten-4-ene-3-ones as 5-.alpha.-reducta

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546 61, 546 14, 514261, 514262, 514256, 514269, 514253, 544264, 544265, 544298, 540 4, A61K 31715

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active

057417954

ABSTRACT:
Compounds of the formula I ##STR1## are inhibitors of 5.alpha.-reductase, and are useful for the treatment of hyperandrogenic disorders such as acne vulgaris, seborrhea, female hirsutism, male pattern baldness, prostatic carcinoma, prostatitis and benign prostatic hyperplasia.

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