Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1975-03-11
1977-08-30
Gerstl, Robert
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
2603433R, 2603457P, 260468H, 260473A, 260514D, 260521B, 260544Y, 260946, 26034622, 542426, 424305, 424308, 424317, C07C17700
Patent
active
040454681
ABSTRACT:
Prostaglandin analogues of the formula: ##STR1## wherein A represents a grouping of the formula: ##STR2## X represents trans-vinylene or ethylene and Y represents cis-vinylene or ethylene, R represents hydrogen or alkyl of 1 through 12 carbon atoms, R.sup.1, R.sup.2 and R.sup.3 represent hydrogen, or alkyl of 1 through 12 carbon atoms or an aryl group, with the proviso that at least one of the symbols R.sup.1, R.sup.2 and R.sup.3 represents an alkyl or aryl group, are new compounds possessing useful pharmacological properties; they are especially useful for the treatment of gastric ulceration.
Kurono Masayasu
Muryobayashi Takashi
Nakai Hisao
Chow Frank S.
Gerstl Robert
Graddis Albert H.
Ono Pharmaceutical Company
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