16-cycloalkyl-7-fluoro-prostacyclins

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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549311, 560121, C07D307935

Patent

active

048087343

ABSTRACT:
16-Cycloalkyl-7-fluoro prostacyclins having a 16 lower alkyl or fluoro substituent useful as blood platelet anti-aggregating agent, vasodilators, cyto protective lowering agents, anti-ulcerogenic agent and for treating peripheral vascular diseases such as schleroderma.

REFERENCES:
patent: 4472428 (1984-09-01), Toru et al.
patent: 4558142 (1985-12-01), Holland et al.
patent: 4634782 (1987-01-01), Holland et al.
patent: 4699989 (1987-10-01), Arata et al.
Bindra et al., Prostaglandin Synthesis, Academic Press Inc., New York, p. 461, 469-470, (1977).

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