16-Alpha-methyl-17 alpha-bromo-1,4-pregnadiene-21-ol-3,20-dione-

Details 16-Alpha-methyl-17 alpha-bromo-1,4-pregnadiene-21-ol-3,20-dione- 16-Alpha-methyl-17 alpha-bromo-1,4-pregnadiene-21-ol-3,20-dione-

1976-01-29

1977-06-21

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26039745, C07j 1700

Patent

active

040310809

ABSTRACT:
There is disclosed 16 alpha-methyl-17 alpha-bromo-1,4-pregnadiene-21-ol-3,20-dione-type compounds of the formula ##STR1## where R is hydrogen or acyl; X is hydrogen, bromine, or fluorine; Y is hydrogen or oxygen; and Z is hydrogen or .alpha.- or .beta.-oriented fluorine. The compounds are useful in treating rheumatoid arthritis and related inflammatory disorders as well as allergic diseases.

REFERENCES:
patent: 3261851 (1966-07-01), Beal et al.
patent: 3350427 (1967-10-01), Gebert et al.

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