[16-Alanine]calcitonin

Details [16-Alanine]calcitonin [16-Alanine]calcitonin

1984-01-13

1985-07-09

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07C10352

Patent

active

045281327

ABSTRACT:
New peptides are disclosed which have biological activity of the same type as known calcitonins and which have an alanine in position 16 instead of the natural leucine or phenylalanine found in that position. Also resin peptides are disclosed which may be converted to peptides having such biological activity; and processes for producing said resin peptides and said calcitonin peptides.

REFERENCES:
patent: 3926938 (1975-12-01), Hughes et al.
patent: 4033940 (1977-07-01), Hughes et al.
patent: 4062815 (1977-12-01), Hughes et al.
patent: 4086221 (1978-04-01), Sakakibara et al.
Noda et al., J. Biochem., 79, 353-359 (1976).

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