15-Substituted prostanoic acids for treating bronchial spasm

Details 15-Substituted prostanoic acids for treating bronchial spasm 15-Substituted prostanoic acids for treating bronchial spasm

1976-04-19

1977-11-22

Rosen, Sam

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424267, 424274, 424305, 424317, A61K 31495, A61K 31215, A61K 3119

Patent

active

040597016

ABSTRACT:
There is disclosed herein a process for relieving bronchial spasm and facilitating breathing in warm-blooded animals which comprises administering to a warm-blooded animal in need thereof an amount sufficient to relieve bronchial spasm and facilitate breathing in said warm-blooded animal of a prostanoic acid of the formula: ##STR1## wherein R is ethynyl, A is --CH.sub.2 --CH.sub.2 -- and B is --CH.sub.2 --CH.sub.2 --; R is ethynyl, A is --CH.sub.2 --CH.sub.2 --, and B is trans --CH=CH--; or R is ethynyl, A is cis --CH=CH--; and B is trans --CH=CH--; and R.sup.1 is hydrogen, alkyl of from 1 to about 6 carbon atoms, alkali metal, or a pharmacologically acceptable cation derived from ammonia or a basic amine.

REFERENCES:
patent: 3773795 (1973-11-01), Bagli et al.
patent: 3816393 (1974-06-01), Hayashi et al.

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