15(R)-5-fluoroprostacyclins, pharmaceutical compositions and ant

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514469, 546269, 549465, A61K 31557, C07D307935

Patent

active

047192208

ABSTRACT:
The present invention provides novel compounds of Formula I ##STR1## which are pharmacologically selectively useful as anti-thrombotic agents with minimal blood pressure lowering activity.

REFERENCES:
patent: 4540801 (1985-09-01), Nysted et al.
patent: 4616034 (1986-10-01), Djuric et al.
Gandolfi et al., "Prostacyclin Analogs: Structure-Activity Relationships", Prostaglandins and Cardiovascular Disease, Raven Press, New York, pp. 183-195 (1981).

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