15-Deoxy-16-hydroxy-16-vinyl or cyclopropyl prostan-1-ols of the

Details 15-Deoxy-16-hydroxy-16-vinyl or cyclopropyl prostan-1-ols of the 15-Deoxy-16-hydroxy-16-vinyl or cyclopropyl prostan-1-ols of the

1978-12-21

1980-06-03

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

2603458P, 2603454P, 2604381, 260463, 2604297, 560 18, 560 72, 560106, 560107, 560162, 560231, 568591, 568816, 568838, 424331, 424343, 556482, 556485, 556436, 568379, 556427, 556441, C07C 4428, C07C 3506

Patent

active

042061512

ABSTRACT:
This disclosure describes novel 15-deoxy-16 hydroxy-16-substituted prostanoic acid analogs in which the C-1 carboxyl is replaced by a primary alcohol and carboxylic acid esters, carbonates and carbomates thereof. The prostanoic carbinols and carboxylic acid esters thereof described herein have utility as bronchodilators as hypotensive agents, and as agents for the control of excessive gastric secretion.

REFERENCES:
patent: 4132738 (1979-01-01), Kluender et al.

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