15-cylobutyl-trans-.DELTA..sup.2 -prostaglandin analogues

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...


Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0


536103, 542426, 560118, 560231, 562500, 568816, 424317, 568367, C07C17700




The present invention relates to prostaglandin analogues of the general formula: ##STR1## [wherein A represents a grouping of the formula: ##STR2## X represents trans-vinylene or ethylene and Y represents cis-vinylene or ethylene, R represents a group of the formula --COOR.sup.4, in which R.sup.4 represents hydrogen or straight- or branched-chain alkyl of 1 to 12 carbon atoms, or a group of the formula --CH.sub.2 OR.sup.5, in which R.sup.5 represents hydrogen or alkylcarbonyl of 2 to 5 carbon atoms and R.sup.1, R.sup.2 and R.sup.3, which may be the same or different, each represent hydrogen, straight- or branched-chain alkyl of 1 to 12 carbon atoms, or an aryl group unsubstituted or substituted by one, two or three substituents selected from alkyl, alkoxy, alkylthio, monoalkylamino and dialkylamino groups and halogen atoms, the alkyl groups or moieties of the said groups containing from 1 to 5 carbon atoms in a straight- or branched-chain, with the proviso that at least one of the symbols R.sup.1, R.sup.2 and R.sup.3 is other than hydrogen and the double bond between C.sub.2 -C.sub.3 is trans] and cyclodextrin clathrates of such prostaglandin analogues and, when R.sup.4 in the group - COOR.sup.4 represents hydrogen, non-toxic salts thereof, which exhibit characteristic prostaglandin-like activities.

patent: 4087620 (1978-05-01), Hayashi et al.


Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.


15-cylobutyl-trans-.DELTA..sup.2 -prostaglandin analogues does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 15-cylobutyl-trans-.DELTA..sup.2 -prostaglandin analogues, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 15-cylobutyl-trans-.DELTA..sup.2 -prostaglandin analogues will most certainly appreciate the feedback.

Rate now


Profile ID: LFUS-PAI-O-2207735

All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.