15-Cyclobutyl-prostaglandins

Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...

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2603473, 2603459P, 424305, 424317, 536 46, 560118, 560 53, 560 59, 560 9, 560 45, 562500, 562469, 562463, 2603433P, 26034622, 542429, 542426, 562452, 562426, 562505, 568807, 568816, C07C17700, A61K 3119, A61K 31215

Patent

active

041171195

ABSTRACT:
Prostaglandin analogues of the formula: ##STR1## wherein A represents a grouping of the formula: ##STR2## X represents trans-vinylene or ethylene and Y represents cis-vinylene or ethylene, R represents hydrogen or alkyl of 1 through 12 carbon atoms, R.sup.1, R.sup.2 and R.sup.3 represent hydrogen, or alkyl of 1 through 12 carbon atoms or an aryl group, with the proviso that at least one of the symbols R.sup.1, R.sup.2 and R.sup.3 represents an alkyl or aryl group, are new compounds possessing useful pharmacological properties; they are especially useful for the treatment of gastric ulceration.

REFERENCES:
patent: 4028396 (1977-06-01), Schaub et al.

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