15-Cycloalkyl-prostaglandins

Details 15-Cycloalkyl-prostaglandins 15-Cycloalkyl-prostaglandins

1975-04-08

1977-07-05

Gerstl, Robert

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260240R, 2603433R, 2603457, 2603458, 2603462R, 260468D, 424305, 424317, C07C17700

Patent

active

040340031

ABSTRACT:
15-Cycloalkyl-prostaglandins of the formula:- ##STR1## wherein A represents a grouping of the formula:- ##STR2## X represents ethylene of cis-vinylene, Y represents ethylene or trans-vinylene, B represents ethylene or trans-vinylene, R represents hydrogen or alkyl of 1 through 4 carbon atoms, R.sup.1 represents cycloalkyl of 4 through 7 carbon atoms, and R.sup.2 represents hydrogen or alkyl of 1 through 12 carbon atoms, are new compounds possessing the useful pharmacological properties typical of prostaglandins; they are of especial interest in the inhibition of blood platelet aggregation.

REFERENCES:
patent: 3849474 (1974-11-01), Abraham et al.

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