15,16-seco-19-nor progestins

Details 15,16-seco-19-nor progestins 15,16-seco-19-nor progestins

1991-01-28

1992-05-26

Mars, Howard T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

558427, 558429, 560256, 568373, 564308, A61K 3121, C07C 69013, C07C25545

Patent

active

051168650

ABSTRACT:
15,16-Seco-19-nor progestins are provided which display elevated progestational activity with a minimum of ancillary hormonal activity. Processes for the preparation of the novel progestins are provided as are methods of use. A preferred method of use is in the suppression of ovulation in the human female.

REFERENCES:
patent: 3109009 (1963-10-01), Nomine et al.
patent: 3206472 (1965-09-01), Nagata
patent: 3275691 (1966-09-01), Goldberg et al.
patent: 3471550 (1969-10-01), Uskokovic
J. S. Baran, J. Med. Chem. 10(6):1039-1047 (1967).
M. A. Bielfeld et al., J. Med. Chem. 12(1):192-195 (1969).
P. F. Sherwin et al., J. Med. Chem. 32(3):651-657 (1989).

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