14273 Receptor, a novel G-protein coupled receptor

Details 14273 Receptor, a novel G-protein coupled receptor 14273 Receptor, a novel G-protein coupled receptor

2006-06-06

2006-06-06

Kemmerer, Elizabeth (Department: 1649)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S006120, C435S007210, C435S069100, C435S252300, C435S320100, C436S501000, C530S350000

Reexamination Certificate

active

07057028

ABSTRACT:
The present invention relates to a newly identified receptor belonging to the superfamily of G-protein-coupled receptors. The invention also relates to polynucleotides encoding the receptor. The invention further relates to methods using the receptor polypeptides and polynucleotides as a target for diagnosis and treatment in receptor-mediated disorders, specifically, cardiovascular diseases, including congestive heart failure. The invention further relates to drug-screening methods using the receptor polypeptides and polynucleotides to identify agonists and antagonists for diagnosis and treatment. The invention further encompasses agonists and antagonists based on the receptor polypeptides and polynucleotides. The invention further relates to procedures for producing the receptor polypeptides and polynucleotides.

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