14-Substituted vincanes

Details 14-Substituted vincanes 14-Substituted vincanes

1976-08-30

1978-10-17

Jiles, Henry R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26029353, C07D51904

Patent

active

041208587

ABSTRACT:
A compound of the formula (I) ##STR1## wherein X stands for a hydrogen atom, an optionally substituted aliphatic or aromatic sulfonyloxy group, a thiocyanato group, an azido group or an amino group optionally mono- or disubstituted by aliphatic, cycloaliphatic, aromatic or araliphatic hydrocarbon groups, acyl, alkyloxycarbonyl, cycloalkyloxycarbonyl, aryloxycarbonyl, aralkyloxycarbonyl, aminocarboimido groups or the substituents of the said amino group may form with the nitrogen atom thereof a five-, six- or seven-membered saturated or unsaturated heterocyclic ring optionally containing a further nitrogen, oxygen or sulfur hetero atom, and a quaternary salt or acid addition salt thereof. The compounds are useful in the treatment of arteriosclerosis and high blood pressure.

REFERENCES:
patent: 3455936 (1969-07-01), Douglas et al.
patent: 3753995 (1973-08-01), Martel et al.
patent: 3987049 (1976-10-01), Plat et al.
patent: 4011330 (1977-03-01), Giudicelli et al.
patent: 4021430 (1977-05-01), Plat et al.
Chemical Abstracts, 54, 16473g (1960), [Bartlett, M. F. et al., Compt. Rend., 249, 1259-1260 (1959)].
Chemical Abstracts, 70, 29146h (1969), [Blaha, K. et al., Coll. Czech. Chem. Comm., 1968, 33(11), 3833-3847].

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