14.alpha.-hydroxy-4-androstene-3,6,17-trione hydrate and process

Details 14.alpha.-hydroxy-4-androstene-3,6,17-trione hydrate and process 14.alpha.-hydroxy-4-androstene-3,6,17-trione hydrate and process

1995-05-30

1997-07-15

Prior, Kimberly J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Cyclopentanohydrophenanthrene ring system containing

C07J 100, C07J 7500

Patent

active

056485077

ABSTRACT:
Provided are stable hydrate crystals of 14.alpha.-hydroxy-4-androstene-3,6,17-trione having a biological activity of human placenta-originating estrodiene synthesis enzyme inhibitory action. These hydrate crystals include two kinds of 14.alpha.-hydroxy-4-androstene-3,6,17-trione hydrate crystals having a diffraction pattern having characteristic peaks at diffraction angles in crystalline powder X-ray diffraction. Processes for producing these hydrate crystals are also provided.

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