14.alpha.,17.alpha.-ethanoestratrienes

Details 14.alpha.,17.alpha.-ethanoestratrienes 14.alpha.,17.alpha.-ethanoestratrienes

1991-05-13

1992-07-28

Mars, Howard T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

552510, 552530, A61K 3105, C01J 5300

Patent

active

051341360

ABSTRACT:
##STR1## New 14.alpha.,17.alpha.-ethano-estratrienes of general formula (I) wherein R.sup.1 is a hydrogen atom, an alkyl or acyl group with 1 to 12 carbon atoms, R.sup.2 is a hydrogen atom or a methyl group, R.sup.3 is a hydrogen atom or an acyl group with 1 to 12 carbon atoms and (a) is either (II) or (III), where R.sup.4 is an alkyl residue in the .alpha. or .beta. position with 1 to 8 carbon atoms or an .alpha.,.beta.-alkenyl residue which may contain several double bonds or an .alpha.,.beta.-alkinyl residue, both with 2 to 8 carbon atoms, are described. Also described is a process for producing them. These new compounds have a marked oestrogenic activity.

REFERENCES:
patent: 4789671 (1988-12-01), Bull et al.

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