13-propylberberine salts

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D45503, A61K 3147

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active

047614773

ABSTRACT:
A 13-propylberberine salt, which is represented by the following general formula (I): ##STR1## wherein X.sup.- means HSO.sub.4 or H.sub.2 PO.sub.4, has strong inhibitory effect against secretion, good stability and high water solubility. Its effects are shown promptly after its oral administration.

REFERENCES:
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Mikes, et al., Chemical Abstracts, vol. 94, 60915c (1981).
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Tolkachev, et al., Chemical Abstracts, vol. 88, 164809p (1978).
Huang, et al., Chemical Abstracts, vol. 94, 20341f (1981).
Nakamura, et al., Chemical Abstracts, vol. 86, 195207d (1977).
The Merck Index, 8th ed., Published by Merck & Co., Inc., Rahway, N. J., pp. 142-143, entry "Berberine", (1968).
The Pharmacopoeia of Japan, 10 ed., English Version, Soc. of Japanese Pharmacopoeia, Yakuji Nippo, Ltd., pp. 1-7 (1982).

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