13-Halo and 13-deoxy derivatives of C-076 compounds

Details 13-Halo and 13-deoxy derivatives of C-076 compounds 13-Halo and 13-deoxy derivatives of C-076 compounds

1977-12-19

1979-11-06

Trousof, Natalie

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424279, 536 17A, C07D49322

Patent

active

041735714

ABSTRACT:
Derivatives of the C-076 compounds are disclosed wherein the 13-position is unsubstituted. The compounds are prepared by removing the glycosyl groups on the 13-position of the C-076 compounds isolated from the fermentation broth of Streptomyces avermitilis, followed by halogenation and subsequent removal of the halogen. The disclosed compounds are antiparasitic, anthelmintic, insecticidal and acaricidal agents.

REFERENCES:
patent: 3950360 (1976-04-01), Aoki et al.
Mishima et al., Tetrahedron Letters, 10, pp. 711-714, 1975.
Jour. of Antibiotics 29(6) Jun. 1976, pp. 76-35 to 76-42 and pp. 76-14 to 76-16.
Derwent Abstracts, 76268w /46 to Sankyo Co.

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