13-Chloro-benzocycloheptapyridoisoquinolines and use as neurolep

Details 13-Chloro-benzocycloheptapyridoisoquinolines and use as neurolep 13-Chloro-benzocycloheptapyridoisoquinolines and use as neurolep

1977-07-21

1982-08-24

Springer, David B.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546 42, A61K 31435, C07D22118

Patent

active

043460909

ABSTRACT:
13-Chloro-octahydrobanzo[6,7]cyclohepta[1,2,3-de]pyrido[2,1-a]isoquinolin-5 -ols, substituted on the piperidine ring with lower alkyl or a cycloalkyl are disclosed. The compounds are useful CNS depressants. Methods for their preparation and use also are disclosed.

REFERENCES:
patent: 3852452 (1974-12-01), Bruderlein et al.
patent: 3861751 (1968-01-01), Humber
Humber et al., Abstract of Papers, 167th A C S M & G., Los Ang. Cal., 1974, Abstract MEOI-5.
Voith et al., Psychopharmacologia (Berl) 42, pp. 11-20 (1975).
Winthrop et al., J. Org.Chem., 27, p. 230 (1962).

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