13,14-Didehydro-11-deoxy-17-phenyl-18,19,20-trinor-PGF.sub.1 .al

Details 13,14-Didehydro-11-deoxy-17-phenyl-18,19,20-trinor-PGF.sub.1 .al 13,14-Didehydro-11-deoxy-17-phenyl-18,19,20-trinor-PGF.sub.1 .al

1977-08-01

1978-09-12

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

260408, 260410, 2604105, 2604109R, 260413, 562465, C07C17700

Patent

active

041139640

ABSTRACT:
This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is replaced by a triple bond. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.

REFERENCES:
derwent Abstract 4723U-B DT 2305044Q (Sep. 7, 1973).
Derwent Abstract 18176y/11 BE 846-080 (Oct. 7, 1977).
Derwent Abstract 61891x/33 DT 2603-172 (May 8, 1976).
Derwent Abstract 59715x/32 BE 839-533 (Jan. 7, 1976).
Derwent Abstract 79219x/42 U.S. 3,984,400 (May 1, 1976).

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