12-aminopyridazinopyrroloisoquinoline compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514247, 544115, 544233, 546 94, C07D48704, A61K 3150, A61K 31535

Patent

active

056145160

ABSTRACT:
The invention relates to new 12-amino-pyridazino-[4',5':3,4]-pyrrolo[2,1-a]isoquinolines of general formula (I) ##STR1## wherein --NR.sub.1 R.sub.2 represents an amino or substituted amino group, and acid addition salts thereof. The new active substances have potential use in pharmaceutical compositions for treating cardiac insufficiency and cerebral metabolic disorders.

REFERENCES:
patent: 4508720 (1985-04-01), Kan et al.
patent: 4694085 (1987-09-01), Losel et al.
patent: 4721711 (1988-01-01), Chambon et al.
Ferrari et al, Chemical Abstracts, vol. 71, No. 81215 (1969).
Losel et al, Chemische Berichte, 118, p. 413 (1985).

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