11a-hydroxy steroid diester

Organic compounds -- part of the class 532-570 series – Organic compounds – Cyclopentanohydrophenanthrene ring system containing

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552602, 552566, 552577, 552575, 552572, 552595, 552594, 514179, 514181, 540111, 540113, 540114, 540120, 540 88, 540 89, 540 10, 540 33, A61K 3156, A61K 3157, C07J 500

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049485334

ABSTRACT:
The present invention relates to 21-(3-carboxy-1-oxopropoxy) -17.alpha.-hydroxy-11.alpha.-(3,3-dimethyl-1-oxobutoxy)pregna-1,4-diene-3, 20 dione and pharmaceutically acceptable salts thereof which are useful steroid prodrugs.

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Kawamura, M., et al., "Pharmaceutical Studies on Water-soluble Cortico-steroid Derivatives, III, Stability of Hydrocortisone-21-Sulfobenzoates and 21-Sulfate in Solution," Yakugaku Zasshi 91, 1971, pp. 871-878.
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