11-Substituted hexahydro-2,6-methano-3-benzazocines

Details 11-Substituted hexahydro-2,6-methano-3-benzazocines 11-Substituted hexahydro-2,6-methano-3-benzazocines

1979-02-05

1981-03-10

Jiles, Henry R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424267, 542400, 542402, 542403, 542429, 542468, 542469, 546 44, 546 46, 546 63, 546 74, C07D22126

Patent

active

042555795

ABSTRACT:
6(eq)-R.sub.4 -1,2,3,4,5,6-Hexahydro-3-R.sub.1 -11(ax)-R.sub.3 -11(eq)-CH.sub.2 Z-2,6-methano-3-benzazocines, useful as analgesic agents and narcotic antagonists, prepared by heating, with formic acid in an organic solvent or with certain ammonium formates in the absence of a solvent, certain 1,2,3,4,4a,5,10,10a-octahydro-2,5-methanobenzo[g]quinolines.

REFERENCES:
patent: 3932422 (1976-01-01), Michne
patent: 4100164 (1978-07-01), Michne
patent: 4119628 (1978-10-01), Lewis et al.
patent: 4148794 (1979-04-01), Lewis et al.

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