Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1978-03-28
1980-10-28
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
260239DD, 2603409R, C07D22320, A61K 3155
Patent
active
042307031
ABSTRACT:
Compounds of the general formula ##STR1## or their salts, esters or amide derivatives; and processes for their preparation. In the formula, R.sub.O represents hydrogen or lower alkyl, R.sub.2 represents hydrogen, halogen or nitro, R.sub.3 represents hydrogen or halogen, and R.sub.4 represents hydrogen or lower alkyl; and when R.sub.O is hydrogen, R.sub.2, R.sub.3 and R.sub.4 are all hydrogens and the group ##STR2## is present at the 2-position. These compounds exhibit superior analgesic and/or anti-inflammatory actions with little gastrointestinal troubles.
REFERENCES:
patent: 3153652 (1964-10-01), Drukker et al.
patent: 3624075 (1971-11-01), Fitzi et al.
patent: 3993757 (1976-11-01), Freedman
Drukker et al., "J. of Heterocyclic Chem.," vol. 2, pp. 276-282 (1965).
Funakoshi Satoshi
Hasegawa Yukio
Mikami Takashi
Minami Nobuyoshi
Miyasaka Katsuhiko
Daus Donald G.
Springer D. B.
Teikoku Hormone Mfg. Co. Ltd.
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