11-ether derivatives of erythromycins

Details 11-ether derivatives of erythromycins 11-ether derivatives of erythromycins

1986-03-10

1989-07-11

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 72, 536 74, A61K 3170, C07H 1708

Patent

active

048472425

ABSTRACT:
11-ether derivatives of erythromycin, and corresponding 9-(optionally substituted)-amino, 9-imino, and 9-(optionally substituted)-oxime derivatives are novel antibacterially active compounds, and can be prepared by alkylation of the 11-hydroxy group under mild conditions.

REFERENCES:
patent: 3780019 (1973-12-01), Wildsmith
patent: 3884904 (1975-05-01), Jones et al.
patent: 4016263 (1977-04-01), Wetzel et al.
March, Advanced Organic Chemistry: Reactions, Mechanisms, and Structure, 1968, p. 316.

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