11-Desoxy-16-aryl-.omega.-tetranorprostaglandins

Details 11-Desoxy-16-aryl-.omega.-tetranorprostaglandins 11-Desoxy-16-aryl-.omega.-tetranorprostaglandins

1975-10-21

1976-10-05

Curtis, Allen B.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260468D, 2603462R, C07C17700

Patent

active

039844005

ABSTRACT:
11-Desoxy-16-aryl-.omega.-tetranorprostaglandins and various intermediates and processes employed in their preparation are disclosed. The novel prostaglandins of this invention have been found to have activity profiles comparable to the parent prostaglandins but they exhibit a greater tissue specificity of action.

REFERENCES:
patent: 3840573 (1974-10-01), Jung et al.
patent: 3932389 (1976-01-01), Johnson et al.
Gandolfi, C., et al., Farmaco [Sci] 27:1125 (1972), (Upjohn Card Index No. 1405).
Pappo, R., et al., Tetrahedron Lett.: 2627 (1972), (Upjohn Card Index No. 1164).
Corey, E. J., et al., Tetrahedron Lett.: 311 (1970), (Upjohn Card Index No. 855).

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