11-Deoxy PGE.sub.2 compounds

Details 11-Deoxy PGE.sub.2 compounds 11-Deoxy PGE.sub.2 compounds

1972-07-24

1978-12-19

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

2603433P, 260410, 2604104R, 26034622, 2604105, 260413, 562503, 424305, 424317, 542426, 560231, C07C17700

Patent

active

041307216

ABSTRACT:
11-Deoxyprostaglandin E and F type compounds, i.e. prostaglandin E and F type compounds in which the 11-hydroxy group is replaced by hydrogen, are disclosed, with processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, labor inducement at term, and wound healing.

REFERENCES:
patent: 3691216 (1972-09-01), Bergstom
patent: 3736319 (1973-05-01), Martel et al.
patent: 3801623 (1974-04-01), Martel et al.
Martel et al., Tetrahedron Letters, 1491 (1972).
Crabbe et al., Tetrahedron Letters, 115 (1972).

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