11 .beta.-substituted progesterone analogs

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai

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514179, 514192, 514177, 514169, 552529, 552597, 552598, 552604, 552558, 552608, 552531, 552520, 552596, 552605, 552514, 552592, 552628, 552532, 540 54, 540 36, 540 37, A61K 3156, C07J 100

Patent

active

049544900

ABSTRACT:
A 11.beta.-aryl-19-norprogesterone steroid of the formula: ##STR1## wherein (i) R.sup.1 is H, C.sub.1-4 alkyl, C.sub.2-4 alkenyl, C.sub.2-4 alkynyl, OH, OC(O)CH.sub.3, or OC(O)R.sup.5, wherein R.sup.5 is C.sub.2-8 alkyl, C.sub.2-8 alkenyl, C.sub.2-8 alkynyl or aryl, R.sub.2 is H, R.sup.3 is H, C.sub.1-4 alkyl, C.sub.2-4 alkenyl or C.sub.2-4 alkynyl, R.sup.4 is H, CH.sub.3, F or Cl, R.sup.6 is H, (CH.sub.3).sub.2 N, CH.sub.3 O, CH.sub.3 CO, CH.sub.3 S, CH.sub.3 SO, CH.sub.3 SO.sub.2, and X is O or NOCH.sub.3 ; or

REFERENCES:
Chemical Abstracts; vol. 100 (1984); #68601k; Philibert et al.
Chemical Abstracts; vol. 108 (1988); #6285s; Philibert et al.

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