11.beta.-FLUOROANDROSTENES

Details 11.beta.-FLUOROANDROSTENES 11.beta.-FLUOROANDROSTENES

1975-02-25

1976-06-29

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26039745, 2603973, C07C 300

Patent

active

039667138

ABSTRACT:
11.beta.-Fluoroandrostenes of the formula ##SPC1##
Wherein R.sub.1 and R.sub.2 are hydrogen atoms, methylene or another C--C bond; R.sub.3 is H or Cl, R.sub.4 is H, F or Cl; and X is carbonyl, .beta.-hydroxymethylene, or an ester or ether thereof or .alpha.-alkyl-.beta.-hydroxymethylene or an ester thereof, possess androgenic activity and can be prepared by the dehalogenation of a corresponding 9.alpha.-halo-11.beta.-F steroid.

REFERENCES:
patent: 3056807 (1962-10-01), Ayer
patent: 3767685 (1973-10-01), Van Vliet
patent: 3875148 (1975-04-01), Elks et al.

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