11-arylsteroid compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai

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514173, 514174, 514175, 514179, 540 17, 540 23, 540107, 540108, 552612, 552644, 552647, A61K 3158, A61K 31585, A61K 3156, C07J 100

Patent

active

049218450

ABSTRACT:
The invention relates to new 11-arylsteroid compounds, having a strong antiprogestin and a weak or nonexistent antiglucocorticoid activity, to processes for preparing said compounds and also to pharmaceutical preparations which contain these derivatives as active constituent, characterized in that said steroids have the following formula: ##STR1## in which R.sub.1 is an aryl group with a ##STR2## group as substituent, X and Y each being separately H or a (1-4 C) hydrocarbyl group or together a (2-C) hydrocarbyl group which forms a 3- to 7-membered ring together with the nitrogen atom;

REFERENCES:
patent: 4386085 (1983-05-01), Teutsch et al.
patent: 4447424 (1984-05-01), Teutsch et al.
patent: 4519946 (1985-05-01), Teutsch et al.
patent: 4609651 (1986-09-01), Rohde et al.
patent: 4634695 (1987-01-01), Torelli et al.
patent: 4780461 (1988-10-01), Neef et al.
Chemical Abstracts; vol. 106 (1987) #84942B; Faustini et al.

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