11,12-cyclic phosphite or phosphate derivatives of erythromycin

Details 11,12-cyclic phosphite or phosphate derivatives of erythromycin 11,12-cyclic phosphite or phosphate derivatives of erythromycin

1997-09-26

1998-07-14

Ambrose, Michael G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 74, C07H 1708

Patent

active

057806047

ABSTRACT:
Disclosed are the antibacterial compounds having the formulas: ##STR1## or pharmaceutically acceptable salts and esters thereof. Also disclosed are the processes for preparing compounds of formulas (I), and II) of the invention, pharmaceutical compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier, as well as a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention.

REFERENCES:
patent: 4331803 (1982-05-01), Watanabe et al.
Recueil. Journal of the Royal Netherlands Chem. Soc., vol. 94, No. 11 (Nov. 1975), pp. 236-238, W. Slawinski et al., "The Structure of Erythromycin A Cyclic Carbonate".

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