10A1 Retroviral packaging cells and uses thereof

Details 10A1 Retroviral packaging cells and uses thereof 10A1 Retroviral packaging cells and uses thereof

1997-02-12

1998-06-16

Chambers, Jasemine C.

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

4351723, 4353201, C12N 510, C12N 1500, C12N 1563

Patent

active

057669457

ABSTRACT:
Retroviral packaging cells produce replication-defective retroviral vector particles capable of binding to Glvr-1 or Ram-1 retroviral receptors on target cells and are useful in gene therapy. The packaging cell employs a vector encoding a 10A1 retroviral env protein and produces the retroviral particles at high titer.

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