Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai
Patent
1992-05-21
1993-04-13
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Cyclopentanohydrophenanthrene ring system doai
514177, 514179, 540 87, 552615, A61K 3158, C07J 100
Patent
active
052023141
ABSTRACT:
A compound of the formula ##STR1## wherein R is selected from the group consisting of alkyl, alkenyl and alkynyl of up to 4 carbon atoms, Y is .dbd.O or ##STR2## R.sub.1 is hydrogen or acyl, n is 0, 1 or 2, D is .dbd.O or ##STR3## and A and B form a second carbon-carbon or an .alpha.-epoxy useful for aromatase inhibition and a process and intermediates for their preparation.
REFERENCES:
patent: 4925834 (1990-05-01), Bohlmann et al.
patent: 5086047 (1992-02-01), Gourvest et al.
Gourvest Jean-Francois
Lesuisse Dominique
Cintins Marianne M.
Kestler Kimberly J.
Roussel Uclaf
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