10-[.omega.-(BENZOYLPIPERIDINYL)ALKYL]PHENOTHIAZINES

Details 10-[.omega.-(BENZOYLPIPERIDINYL)ALKYL]PHENOTHIAZINES 10-[.omega.-(BENZOYLPIPERIDINYL)ALKYL]PHENOTHIAZINES

1976-04-20

1977-05-03

Randolph, John D.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

260243A, 2602938, C07D41706, A61K 2700

Patent

active

040215520

ABSTRACT:
10-[.omega.-(Benzoylpiperidinyl)alkyl]phenothiazines having the formula ##STR1## wherein R is hydrogen, chloro, bromo, trifluoromethyl, lower alkoxy, acetyl, sulfamoyl, or dimethylsulfamoyl, R.sup.1 is hydrogen, chloro, bromo, fluoro, trifluoromethyl, lower alkyl or lower alkoxy and n is 2, 3 or 4 are disclosed. Methods for the preparation of the compounds are described. The compounds possess tranquilizing activity and are useful as tranquilizing agents in mammals.

REFERENCES:
patent: 3225037 (1965-12-01), Zenitz et al.
patent: 3637660 (1972-01-01), Eriksoo et al.
Schenker-Herbst, Drug Research, vol. 5, pp. 288 to 289 and 419 to 426, Birkhauser Verlag Basel und Stuttgart, (1963).
Chemical Abstracts, vol. 72, Abst. No. 100535h, (1970), (Abst. of German Offen. 1,930,818).

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