Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1978-04-06
1979-01-02
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
A61K 31435
Patent
active
041327942
ABSTRACT:
Novel 10-imidoylphenoxazines and 10-imidoylacridans are prepared by reacting a phenoxazine or acridan having optional substituents selected from the group consisting of trifluoromethyl, halogen, dihalogen, alkyl or alkoxy with an imidoyl halide prepared in situ from amides and lactams. Illustrative embodiments are 10-(5-methyl-1-pyrrolin-2-yl)phenoxazine and 9,9-dimethyl-10-(5-methyl-1-pyrrolin-2-yl)acridan. The imidoylphenoxazines and imidoylacridan products are generally useful as smooth muscle relaxants.
REFERENCES:
patent: 3498986 (1970-03-01), Meisels et al.
patent: 3770727 (1973-11-01), Brack
Moskoukina et al., Chem. Abst. vol. 73-14649n (1970).
Lobeck, Jr. Walter G.
Wu Yao H.
Carnahan Robert E.
Friedman Stanley J.
Mead Johnson & Company
Uloth Robert H.
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