10-AZA-9-deoxo-11-deoxy-erythromycin A and derivatives combined

Details 10-AZA-9-deoxo-11-deoxy-erythromycin A and derivatives combined 10-AZA-9-deoxo-11-deoxy-erythromycin A and derivatives combined

1996-03-25

1997-06-24

Wilson, James O.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

435 34, 435 18, 435 29, 435 39, 435 40, 435 51, 536 72, A61K 3170, C07H 1708

Patent

active

056417535

ABSTRACT:
Pharmaceutical compositions of an erythromycin derivative combined with sulfisoxazole according to the structural formulas: ##STR1## where R is hydrogen, C1-C10 alkylcarbonyl or C1-C10 alkyl wherein the substituent is amino or cyano; R1 and R2 are independently hydrogen, hydroxyl or amino; and the pharmaceutical salts and esters thereof.

REFERENCES:
Tarpay et al., Antimicrobial Agents and Chemotherapy, vol. 22, No. 1, pp. 145-147 (1982).
Hughes et al., J. of Infectious Diseases, vol. 170, No. 1, pp. 906-911, (1994).
Doern et al., Antimicrobial Agents and Chemotherapy, vol. 32, No. 2, pp. 180-185 (1988).

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