10,11-Furo-derivatives of cyproheptadine

Details 10,11-Furo-derivatives of cyproheptadine 10,11-Furo-derivatives of cyproheptadine

1975-01-30

1976-08-10

Trousof, Natalie

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

26029358, 26029362, C07D40510

Patent

active

039742857

ABSTRACT:
10,11-Furo and 10,11-bis-(hydroxyalkyl) derivatives of cyproheptadine are disclosed having anticholinergic activity but with diminished or eliminated antiserotonin and antihistamine activity. Also disclosed are processes for the preparation of such compounds; pharmaceutical compositions comprising such compounds, and methods of treatment comprising administering such compounds and compositions.

REFERENCES:
patent: 3014911 (1961-12-01), Engelhardt
patent: 3470188 (1969-09-01), Kaiser et al.
patent: 3838123 (1974-09-01), Viterbo et al.
Tochtermann et al. Chem. Abst. 1968, vol. 69, No. 96429v.

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