10,11-Dihydro-10,10,11,11 -tetrafluoro-5H-dibenzo[a,d]cyclohepte

Details 10,11-Dihydro-10,10,11,11 -tetrafluoro-5H-dibenzo[a,d]cyclohepte 10,11-Dihydro-10,10,11,11 -tetrafluoro-5H-dibenzo[a,d]cyclohepte

1974-02-01

1976-04-13

Hines, Robert V.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260349, 260453A, 260471C, 260475FR, 260515A, 260516, 2605011, 260556AR, 2605708TC, 260607B, 260609R, 260612R, 260618F, 260649F, 260520B, 260590FB, 424316, 424330, C07C 8729

Patent

active

039504239

ABSTRACT:
Tetrafluoro derivatives of 10,11-dihydrodibenzo[a,d]cyclohepten-5-aminomethyl compounds and the corresponding N-substituted derivatives thereof, useful as antiarrhythmic agents, are prepared from tetrafluoro derivatives of 10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-one by reduction to the corresponding 5-ol compound and subsequently converting said 5-ol compound to the corresponding 5-halo and the 5-aminomethyl derivatives by reactions known in the prior art.

REFERENCES:
patent: 3707562 (1972-12-01), Schindler et al.

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