10,11,Di hydro-N-alkoxycarbonyl-10,10,11,11-tetrafluoro-5H-diben

Details 10,11,Di hydro-N-alkoxycarbonyl-10,10,11,11-tetrafluoro-5H-diben 10,11,Di hydro-N-alkoxycarbonyl-10,10,11,11-tetrafluoro-5H-diben

1975-04-17

1977-04-26

Raymond, Richard L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424300, C07C12506

Patent

active

040200965

ABSTRACT:
Tetrafluoro derivatives of 10,11-dihydrodibenzo[a,d]cyclohepten-5-aminomethyl compounds and the corresponding N-substituted derivatives thereof, useful as antiarrhythmic agents, are prepared from tetrafluoro derivatives of 10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-one by reduction to the corresponding 5-ol compound and subsequently converting said 5-ol compound to the corresponding 5-halo and the 5-aminomethyl derivatives by reactions known in the prior art.

REFERENCES:
patent: 3324170 (1967-06-01), Kollonitsch
patent: 3372196 (1968-03-01), Engelhardt
patent: 3917669 (1975-11-01), Kyburz et al.
patent: 3922305 (1975-11-01), Engelhardt

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